中医药
样例:中药指纹图谱质控技术的意义和作用
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- ress has been made during the recent 20 years. For example, in the 1963 version of Chinese Pharmacopoeia, there were only sources and appearance identification for Chinese herbal medicines and only prescription and preparation for Chinese patent medicines but without any testing items; 14 years later, in the 1977 version, the microscopic identification was used widely in the Pharmacopoeia; from the 1985 version, chromatography and spectroscopy had been adopted for quality control of traditional Chinese medicines; the application of specific measures technologies, determined components and required species all grew continuously; in the latest 2000 version, 308 kinds of measured varieties were included in the Pharmacopoeia. To take the known main components or effective components as the indicator used in testing control is a great breakthrough and progress compared with the past. But in view of traditional Chinese medicine, the control of indicator components is difficult to really control the efficacy of traditional Chinese medicines. Chinese dialectical therapy is in accordance with the ingredients instead of some certain chemical component. Ephedrine and ephedra, glycyrrhizic acid and glycyrrhiza, ginsenoside and ginseng, etc., are two different things in view of traditional Chinese medicine.
The efficacy of “invigorating qi”, “activating blood”, “warming interior”, “stimulating surface”, “nourishing yin”, “strengthening spleen”, etc. of traditional Chinese medicines are the results of overall effects of the internal substance group in Chinese herbal medicine pieces or patent medicine prescriptions. The whole situation of the internal substance group, including the number of substances, the mass of substances and the difference of composition proportions, could all affect the efficacy. There is a theory saying that “the prescription could be initiated, while the amount could not” in traditional Chinese medicine, that is to say, the efficacy of prescription depends not only on the ingredients that make up the prescription, but also on the absolute amount and compatibility ratio of each ingredient. Therefore, the composition of the prescription could be initiated, but the amount of each ingredient is the core secret of the technology, which could not be announced. For example, the surface stimulator “cinnamon twig decoction ” in the Zhang Zhongjing’s Treatise on Febrile Diseases is composed of cassia twig, peony, ginger, prepared licorice and jujube; only by doubling the amount of peony and adding maltose, it becomes a “Xiaojianzhong decoction” that is deficiency-reinforcing, cold-dispelling and Jianzhong (spleen and stomach) -warming. As a result, to control the efficacy of traditional Chinese medicine should not be focused on certain one or two components, but on the overall substance group of the prescription.上一页 [1] [2] [3]
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